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To determine if dantrolene increases AO mediated exon skipping of clinically relevant DMD mutations, we created cell culture models from patients potentially amenable to exon 45 skipping Center for Duchenne Muscular Dystrophy 10003 CDMD1003, deletion of exons 46 51; and CDMD1006, deletion of exons 46 47 or exon 44 skipping CDMD1015, deletion of exon 45 priligy SERMs can be distinguished from each other in reproductive tissue, particularly the uterus, by their activity profile